Abstract
The current study was designed to investigate the protective role of Phoenix dactylifera (date palm) water extract (DPE) against oxidative injury induced by different concentrations of hexavalent chromium (CrVI) in liver and muscles of Tilapia nilotica (Oreochromis niloticus) fish in vitro. Results demonstrated that CrVI caused a significant concentration-dependent inhibition in glutathione S-transferase, superoxide dismutase and catalase activities as well as glutathione content. In addition, inhibition in transaminases and alkaline phosphatase activities were observed. While, thiobarbituric acid reactive substances levels in liver and muscles homogenate were increased. On the other hand, homogenates treated with DPE alone improve the antioxidant status and liver function biomarkers. Moreover, homogenate pretreated with DPE then exposed to CrVI showed marked modulation in lipid peroxidation, enzyme activities and protein content as compared to their respective CrVI treated ones. Conclusively, Phoenix dactylifera might have a potential protective role against CrVI toxicity.
